Title : Mechanism of group IVA cytosolic phospholipase A(2) activation by phosphorylation.

Pub. Date : 2003 Oct 17

PMID : 12885780






1 Functional Relationships(s)
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1 When HEK293 cells transfected with cPLA2 and mutants were stimulated with ionomycin, the wild type and S505E translocated to the perinuclear region and caused the arachidonic acid release at 0.4 microm Ca2+, whereas S505A showed no membrane translocation and little activity to release arachidonic acid. Ionomycin phospholipase A2 group IVA Homo sapiens