Title : NFkappaB regulates plasma apolipoprotein A-I and high density lipoprotein cholesterol through inhibition of peroxisome proliferator-activated receptor alpha.

Pub. Date : 2003 Oct 3

PMID : 12882972






1 Functional Relationships(s)
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1 This IkappaBalpha-induced apoA-I increase was blocked by preincubation with MK886, a selective inhibitor of peroxisome proliferator-activated receptor alpha (PPARalpha), suggesting that NFkappaB inactivation induces apoA-I through activation of PPARalpha. MK-886 nuclear factor kappa B subunit 1 Homo sapiens