Title : Involvement of the extracellular signal regulated kinase pathway in hydrocarbon-induced reactive oxygen species formation in human neutrophil granulocytes.

Pub. Date : 2003 Jul 15

PMID : 12878040






1 Functional Relationships(s)
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1 Based on these findings we propose a mechanism involving tyrosine kinases, PI3 kinase, and the ERK1/2 pathway, leading to activation of the NADPH oxidase and production of ROS in neutrophils stimulated by organic solvents. Reactive Oxygen Species mitogen-activated protein kinase 3 Homo sapiens