Title : Identification of a novel proline-arginine motif involved in CIN85-dependent clustering of Cbl and down-regulation of epidermal growth factor receptors.

Pub. Date : 2003 Oct 10

PMID : 12874286






2 Functional Relationships(s)
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1 Identification of a novel proline-arginine motif involved in CIN85-dependent clustering of Cbl and down-regulation of epidermal growth factor receptors. Proline Cbl proto-oncogene Homo sapiens
2 This motif was indispensable for CIN85 binding to Cbl/Cbl-b, to other CIN85 SH3 domains" effectors, and for mediating an intramolecular interaction between the SH3-A domain and the proline-rich region of CIN85. Proline Cbl proto-oncogene Homo sapiens