Pub. Date : 2003 Aug
PMID : 12853767
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | PURPOSE: We identify whether tachyphylaxis and priapism effects of sildenafil are related to regulation of phosphodiesterase-5 (PDE-5) expression. | Sildenafil Citrate | phosphodiesterase 5A | Homo sapiens |
| 2 | RESULTS: Up-regulation of PDE-5 was noted in CSMCs treated with 25 microM sildenafil for 7 days. | Sildenafil Citrate | phosphodiesterase 5A | Homo sapiens |
| 3 | PDE-5 messenger RNA and protein levels were significantly increased in the 7-day sildenafil treated cultures. | Sildenafil Citrate | phosphodiesterase 5A | Homo sapiens |