Title : High throughput screening identifies novel inhibitors of Escherichia coli dihydrofolate reductase that are competitive with dihydrofolate.

Pub. Date : 2003 Aug 4

PMID : 12852950






1 Functional Relationships(s)
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1 Secondary screening of these revealed twelve molecules that were competitive with dihydrofolate, nine of which have not been previously characterized as inhibitors of dihydrofolate reductase. dihydrofolate Dihydrofolate reductase Escherichia coli