Title : Valdecoxib: a review.

Pub. Date : 2003 Mar

PMID : 12852704






1 Functional Relationships(s)
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1 BACKGROUND: Traditional nonsteroidal anti-inflammatory drugs (NSAIDs) such as diclofenac, ibuprofen, naproxen, and related agents are nonselective inhibitors of both cyclooxygenase-1 (COX-1) and COX-2, which catalyze prostaglandin synthesis. Ibuprofen mitochondrially encoded cytochrome c oxidase II Homo sapiens