Title : Sodium salicylate induces apoptosis in HCT116 colorectal cancer cells through activation of p38MAPK.

Pub. Date : 2003 Aug

PMID : 12851702






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1 Here we show that in HCT116 colon carcinoma cells, 10 mM sodium salicylate induces caspase-3 activation and degradation of its substrates, poly(ADP-ribose) polymerase (PARP), beta-catenin, and retinoblastoma (Rb). Sodium Salicylate caspase 3 Homo sapiens