Title : Arsenic trioxide selectively induces early and extensive apoptosis via the APO2/caspase-8 pathway engaging the mitochondrial pathway in myeloma cells with mutant p53.

Pub. Date : 2003 Jul-Aug

PMID : 12851490






2 Functional Relationships(s)
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1 Arsenic trioxide selectively induces early and extensive apoptosis via the APO2/caspase-8 pathway engaging the mitochondrial pathway in myeloma cells with mutant p53. Arsenic Trioxide caspase 8 Homo sapiens
2 In cells expressing mutated p53, ATO induced, G2/M arrest and activation caspase 8 and 3 and rapid and extensive apoptosis. Arsenic Trioxide caspase 8 Homo sapiens