Title : Reconstitution of sterol-regulated endoplasmic reticulum-to-Golgi transport of SREBP-2 in insect cells by co-expression of mammalian SCAP and Insigs.

Pub. Date : 2003 Sep 12

PMID : 12842885






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 In sterol-treated cells, the SCAP/SREBP complex binds to Insig-1 or Insig-2, which retains the complex in the ER, blocking SREBP processing and decreasing lipid synthesis. Sterols insulin induced gene 1 Homo sapiens