Title : Effect of phorbol ester and cytokines on matrix metalloproteinase and tissue inhibitor of metalloproteinase expression in tumor and normal cell lines.

Pub. Date : 1992

PMID : 1284126






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 In contrast, MMP-3, MMP-9 and TIMP-1 activities were markedly stimulated by TPA in most of the tumor cell lines and human umbilical vein endothelial cells (HUVEC), whereas the fibroblast lines were minimally stimulated or unresponsive to TPA. Tetradecanoylphorbol Acetate TIMP metallopeptidase inhibitor 1 Homo sapiens
2 TPA-mediated stimulation of MMP-9 and TIMP-1 activity was blocked by staurosporine, an inhibitor of protein kinase C (PKC). Tetradecanoylphorbol Acetate TIMP metallopeptidase inhibitor 1 Homo sapiens