Title : Effects of metal ions on activity of plasmin.

Pub. Date : 2003 Summer

PMID : 12835493






2 Functional Relationships(s)
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1 In the presence of Zn2+, Cu2+, Cd2+, and Au+ in the incubation mixture at the concentrations of 1 x 10(-5) - 1x 10(-3) M, the amidolytic plasmin activity was strongly inhibited, whereas Ca2+ and Mg2+ at the same concentrations were not effective. Gold plasminogen Homo sapiens
2 Incubation of plasmin with Zn2+ or Cu2+ (at the concentration of 5 x 10(-4) M) resulted in complete loss of its proteolytic action on fibrinogen, whereas Cd2+ and Au+ under the same conditions only partially inhibited this process. Gold plasminogen Homo sapiens