Title : Regulation of cyclooxgenase-2 mRNA stability by taxanes: evidence for involvement of p38, MAPKAPK-2, and HuR.

Pub. Date : 2003 Sep 26

PMID : 12826679






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 We investigated the effects of taxanes (docetaxel and paclitaxel) on cyclooxygenase-2 (COX-2) transcription and mRNA stability in human mammary epithelial cells. Docetaxel prostaglandin-endoperoxide synthase 2 Homo sapiens
2 We investigated the effects of taxanes (docetaxel and paclitaxel) on cyclooxygenase-2 (COX-2) transcription and mRNA stability in human mammary epithelial cells. Docetaxel prostaglandin-endoperoxide synthase 2 Homo sapiens
3 As reported previously for paclitaxel, docetaxel stimulated COX-2 transcription by an AP-1-dependent mechanism. Docetaxel prostaglandin-endoperoxide synthase 2 Homo sapiens