Title : Memory T cells of a patient with follicular thyroid carcinoma recognize peptides derived from mutated p21 ras (Gln-->Leu61).

Pub. Date : 1992 Nov

PMID : 1282032






2 Functional Relationships(s)
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1 Point mutations in ras genes resulting in substitutions of amino acid Gly in positions 12 and 13, and Gln in position 61 of the ras gene product p21, are commonly found in human tumors. Glutamine H3 histone pseudogene 16 Homo sapiens
2 Here we report that CD4+ T cells of memory type (CD45RO+) from a patient with a follicular thyroid carcinoma respond against a synthetic peptide derived from aberrant p21 ras having a Gln-->Leu substitution at position 61. Glutamine H3 histone pseudogene 16 Homo sapiens