Title : Potentiation of tumor necrosis factor-alpha expression by YC-1 in alveolar macrophages through a cyclic GMP-independent pathway.

Pub. Date : 2003 Jul 1

PMID : 12818375






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1 Using cultured rat alveolar NR 8383 macrophages, this study investigated the effect of YC-1 [3-(5"-hydroxymethyl-2"-furyl)-1-benzyl indazole], a soluble guanylyl cyclase (sGC) activator, on the production of tumor necrosis factor-alpha (TNF alpha). 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole tumor necrosis factor Rattus norvegicus