Title : Colchicine down-regulates cytochrome P450 2B6, 2C8, 2C9, and 3A4 in human hepatocytes by affecting their glucocorticoid receptor-mediated regulation.

Pub. Date : 2003 Jul

PMID : 12815172






1 Functional Relationships(s)
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1 Colchicine (COL) decreased both basal and rifampicin- and phenobarbital-inducible expression of CYP2B6, CYP2C8/9, and CYP3A4. Phenobarbital cytochrome P450 family 3 subfamily A member 4 Homo sapiens