Title : Suppression by polycyclic compounds of the conversion of human amylin into insoluble amyloid.

Pub. Date : 2003 Sep 15

PMID : 12812521






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Of the compounds investigated, incubation of human amylin with a 20-fold molar excess of either Congo Red or Acridine Orange resulted in significant inhibition in the rate of amyloid formation. Congo Red islet amyloid polypeptide Homo sapiens
2 With Congo Red, maximal inhibition effectively occurred at a 1:1 molar ratio or greater over human amylin, whereas inhibition by Acridine Orange was dose-dependent. Congo Red islet amyloid polypeptide Homo sapiens