Title : Practical issues in the development of argatroban: a perspective.

Pub. Date : 2002

PMID : 12811013






5 Functional Relationships(s)
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Protein Name
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1 Argatroban was the very first antithrombin agent that was approved for clinical use. argatroban serpin family C member 1 Homo sapiens
2 Unlike other antithrombin drugs, argatroban is a reversible antithrombin agent. argatroban serpin family C member 1 Homo sapiens
3 Unlike other antithrombin drugs, argatroban is a reversible antithrombin agent. argatroban serpin family C member 1 Homo sapiens
4 At a comparable ACT (300 s), argatroban produces much stronger inhibition of thrombin generation as measured by F(1.2) and thrombin-antithrombin complex generation. argatroban serpin family C member 1 Homo sapiens
5 The pharmacological profile of argatroban is unique as this antithrombin drug not only inhibits thrombogenesis but also modulates cellular functions. argatroban serpin family C member 1 Homo sapiens