Title : Synthetic diacylglycerols (DAG) and DAG-lactones as activators of protein kinase C (PK-C).

Pub. Date : 2003 Jun

PMID : 12809530






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 We have developed a series of 4,4-disubstituted-gamma-butyrolactones, which contain a constrained glycerol backbone (DAG-lactones) and behave as potent and selective activating ligands of PK-C with affinities that approach those of the structurally complex natural product agonists, such as the phorbol esters. Glycerol proline rich transmembrane protein 2 Homo sapiens