Pub. Date : 2003 Jul
PMID : 12807727
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Molecular mechanisms of curcumin-induced cytotoxicity: induction of apoptosis through generation of reactive oxygen species, down-regulation of Bcl-XL and IAP, the release of cytochrome c and inhibition of Akt. | Curcumin | BCL2 like 1 | Homo sapiens |
2 | Curcumin causes dose-dependent apoptosis and DNA fragmentation of Caki cells, which is preceded by the sequential dephosphorylation of Akt, down-regulation of the anti-apoptotic Bcl-2, Bcl-XL and IAP proteins, release of cytochrome c and activation of caspase 3. | Curcumin | BCL2 like 1 | Homo sapiens |