Title : Influence of glucocorticoid, aspirin, and gamma globulin on interleukin-6 production in the hepatoma cell line.

Pub. Date : 1992 Jul-Aug

PMID : 1280631






3 Functional Relationships(s)
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1 The current study was designed to observe the effects of drugs used for the treatment of inflammatory diseases (glucocorticoid, aspirin, and gamma globulin) on interleukin 6 (IL-6) production in the liver which may be involved in acute phase protein stimulation. Aspirin interleukin 6 Homo sapiens
2 At 48 h after addition of glucocorticoid and aspirin, there was a suppression of IL-6 activity in the culture supernatants, which was associated with a decrease of mRNA level in the cells. Aspirin interleukin 6 Homo sapiens
3 These data demonstrate that glucocorticoid and aspirin are potent regulators of IL-6 synthesis in the hepatoma cell. Aspirin interleukin 6 Homo sapiens