Title : Pranlukast inhibits NF-kappa B activation in human monocytes/macrophages and T cells.

Pub. Date : 2003 Jun

PMID : 12801316






1 Functional Relationships(s)
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1 The inhibitory effects of pranlukast and MK-571, which is an LTD4 receptor-selective antagonist, on TNF-alpha-induced NF-kappa B activation was evaluated by Western blotting and flow cytometry, and those on lipopolysaccharide (LPS)-induced interleukin-6 (IL-6) production in peripheral blood mononuclear cells (PBMC) were evaluated by enzyme-linked immunosorbent assaying. verlukast cysteinyl leukotriene receptor 1 Homo sapiens