Title : Mutant huntingtin increases nuclear corepressor function and enhances ligand-dependent nuclear hormone receptor activation.

Pub. Date : 2003 May

PMID : 12799135






1 Functional Relationships(s)
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1 Interestingly, using GST pull-down assays we found that a mutant Htt exon 1 construct with 53 polyglutamine (HD53Q) did not bind to NCoR in a polyglutamine-dependent fashion. polyglutamine huntingtin Rattus norvegicus