Title : Myeloperoxidase has directly-opposed effects on nitration reaction--study on myeloperoxidase-deficient patient and myeloperoxidase-knockout mice.

Pub. Date : 2003 May

PMID : 12797467






4 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Myeloperoxidase (MPO) catalyzes a nitration reaction to form nitrotyrosine in the presence of high nitrite, the metabolite of NO. Nitrites myeloperoxidase Homo sapiens
2 Myeloperoxidase (MPO) catalyzes a nitration reaction to form nitrotyrosine in the presence of high nitrite, the metabolite of NO. Nitrites myeloperoxidase Homo sapiens
3 Human leukocyte was shown to cause phenolic nitration using released MPO as a catalyst in the presence of nitrite. Nitrites myeloperoxidase Homo sapiens
4 We conclude that MPO may act predominantly to scavenge nitrotyrosine under physiological nitrite condition, and protect against injurious effect of nitrotyrosine. Nitrites myeloperoxidase Homo sapiens