Pub. Date : 1992 Nov 15
PMID : 1279700
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Using an FK506 affinity column to identify mammalian immunosuppressant-binding proteins, we identified an immunophilin with an apparent M(r) approximately 55,000, which we have named FKBP52. | Tacrolimus | FKBP prolyl isomerase 4 | Homo sapiens |
2 | Recombinant hFKBP52 has peptidyl-prolyl cis-trans isomerase activity that is inhibited by FK506 and rapamycin and an FKBP12-like consensus sequence that probably defines the immunosuppressant-binding site. | Tacrolimus | FKBP prolyl isomerase 4 | Homo sapiens |