Title : Coordinate regulation of IFN consensus sequence-binding protein and caspase-1 in the sensitization of human colon carcinoma cells to Fas-mediated apoptosis by IFN-gamma.

Pub. Date : 2003 Jun 15

PMID : 12794166






2 Functional Relationships(s)
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1 In this study, we examined the molecular basis by which IFN-gamma differentially sensitized human primary and metastatic colon carcinoma cells to Fas-mediated apoptosis. ammonium ferrous sulfate interferon gamma Homo sapiens
2 Functional studies demonstrated that both caspase-1 and ICSBP were involved in Fas-mediated apoptosis following IFN-gamma sensitization, but proceeded via two distinct pathways. ammonium ferrous sulfate interferon gamma Homo sapiens