Title : Mutations of p53 gene in hepatocellular carcinoma: roles of hepatitis B virus and aflatoxin contamination in the diet.

Pub. Date : 1992 Nov 4

PMID : 1279184






4 Functional Relationships(s)
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1 Mutations of p53 gene in hepatocellular carcinoma: roles of hepatitis B virus and aflatoxin contamination in the diet. Aflatoxins tumor protein p53 Homo sapiens
2 These reports suggested an association of p53 mutations with high levels of aflatoxin in the diet. Aflatoxins tumor protein p53 Homo sapiens
3 PURPOSE: The purpose of this study was to evaluate the relationship of p53 gene mutation to high or low levels of aflatoxin in the diet and to HBV infection. Aflatoxins tumor protein p53 Homo sapiens
4 CONCLUSION: Mutations of the tumor suppressor gene p53 in hepatocellular carcinomas are not limited to patients from geographic regions where the ingestion of aflatoxin is high. Aflatoxins tumor protein p53 Homo sapiens