Title : Combination treatment with azidothymidine and granulocyte colony-stimulating factor in children with human immunodeficiency virus infection.

Pub. Date : 1992 Nov

PMID : 1279153






4 Functional Relationships(s)
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1 We evaluated the effect of subcutaneously administered granulocyte colony-stimulating factor (G-CSF) in pediatric patients whose absolute neutrophil count was less than 0.8 x 10(9)/L during AZT therapy despite dosage reductions to 120 mg/m2 every 6 hours. Zidovudine colony stimulating factor 3 Homo sapiens
2 With doses of G-CSF ranging from 1 to 20 micrograms/kg per day, 17 of 19 patients were able to tolerate AZT at a dose of 120 to 180 mg/m2 every 6 hours. Zidovudine colony stimulating factor 3 Homo sapiens
3 We conclude that G-CSF therapy enables patients who have had AZT-related neutropenia to receive therapeutic doses of AZT. Zidovudine colony stimulating factor 3 Homo sapiens
4 We conclude that G-CSF therapy enables patients who have had AZT-related neutropenia to receive therapeutic doses of AZT. Zidovudine colony stimulating factor 3 Homo sapiens