Title : Effects of rofecoxib or naproxen vs placebo on Alzheimer disease progression: a randomized controlled trial.

Pub. Date : 2003 Jun 4

PMID : 12783912






1 Functional Relationships(s)
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1 OBJECTIVE: To determine whether treatment with a selective cyclooxygenase (COX) -2 inhibitor (rofecoxib) or a traditional nonselective NSAID (naproxen) slows cognitive decline in patients with mild-to-moderate AD. rofecoxib mitochondrially encoded cytochrome c oxidase II Homo sapiens