Pub. Date : 2003 Jun
PMID : 12773168
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | hCE1 catalyses the hydrolysis of heroin and cocaine, and the transesterification of cocaine in the presence of ethanol to the toxic metabolite cocaethylene. | Cocaine | carboxylesterase 1 | Homo sapiens |
2 | hCE1 catalyses the hydrolysis of heroin and cocaine, and the transesterification of cocaine in the presence of ethanol to the toxic metabolite cocaethylene. | Cocaine | carboxylesterase 1 | Homo sapiens |
3 | We have determined the crystal structures of hCE1 in complex with either the cocaine analogue homatropine or the heroin analogue naloxone. | Cocaine | carboxylesterase 1 | Homo sapiens |