Pub. Date : 2003 Jun 6
PMID : 12757841
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Eugenol suppresses cyclooxygenase-2 expression in lipopolysaccharide-stimulated mouse macrophage RAW264.7 cells. | Eugenol | prostaglandin-endoperoxide synthase 2 | Mus musculus |
| 2 | In addition, eugenol suppressed the cyclooxygenase-2 (COX-2) gene expression in LPS-stimulated mouse macrophage cells. | Eugenol | prostaglandin-endoperoxide synthase 2 | Mus musculus |
| 3 | In addition, eugenol suppressed the cyclooxygenase-2 (COX-2) gene expression in LPS-stimulated mouse macrophage cells. | Eugenol | prostaglandin-endoperoxide synthase 2 | Mus musculus |
| 4 | On the line of COX-2 playing an important role in colon carcinogenesis further study was designed to investigate the effect of eugenol on the growth and COX-2 expression in HT-29 human colon cancer cells. | Eugenol | prostaglandin-endoperoxide synthase 2 | Mus musculus |
| 5 | Eugenol inhibited the proliferation of HT-29 cells and the mRNA expression of COX-2, but not COX-1. | Eugenol | prostaglandin-endoperoxide synthase 2 | Mus musculus |
| 6 | This result suggests that eugenol might be a plausible lead candidate for further developing the COX-2 inhibitor as an anti-inflammatory or cancer chemopreventive agent. | Eugenol | prostaglandin-endoperoxide synthase 2 | Mus musculus |