Title : Thyroid Ca2+/NADPH-dependent H2O2 generation is partially inhibited by propylthiouracil and methimazole.

Pub. Date : 2003 Jun

PMID : 12755690






1 Functional Relationships(s)
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1 Decreased H2O2 availability may be another mechanism of inhibition of thyroperoxidase activity produced by thioureylene compounds, as propylthiouracil (PTU) and methimazole (MMI) are antioxidant agents. Hydrogen Peroxide thyroid peroxidase Homo sapiens