Title : A transforming growth factorbeta1 signal peptide variant increases secretion in vitro and is associated with increased incidence of invasive breast cancer.

Pub. Date : 2003 May 15

PMID : 12750287






1 Functional Relationships(s)
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Protein Name
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1 Transfections of HeLa cells with constructs encoding either the Pro or Leu forms of TGFbeta1 and driven by the cytomegalovirus promoter indicate that the signal peptide with Pro at residue 10 causes a 2.8-fold increase in secretion compared with the Leu form. Leucine transforming growth factor beta 1 Homo sapiens