Pub. Date : 2003 Jun
PMID : 12730686
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | They possess both sequence-specific binding and proline cis-trans isomerase activities, as exemplified by the interaction between cyclophilin A (CypA) and the HIV-1 CA protein. | Proline | peptidylprolyl isomerase A | Homo sapiens |
| 2 | They possess both sequence-specific binding and proline cis-trans isomerase activities, as exemplified by the interaction between cyclophilin A (CypA) and the HIV-1 CA protein. | Proline | peptidylprolyl isomerase A | Homo sapiens |
| 3 | Here, we report crystal structures of CypA in complex with HIV-1 CA protein variants that bind preferentially with the substrate proline residue in either the cis or the trans conformation. | Proline | peptidylprolyl isomerase A | Homo sapiens |
| 4 | CypA Arg55 guanidinium group probably facilitates catalysis by anchoring the substrate proline oxygen and stabilizing sp3 hybridization of the proline nitrogen in the transition state. | Proline | peptidylprolyl isomerase A | Homo sapiens |
| 5 | CypA Arg55 guanidinium group probably facilitates catalysis by anchoring the substrate proline oxygen and stabilizing sp3 hybridization of the proline nitrogen in the transition state. | Proline | peptidylprolyl isomerase A | Homo sapiens |