Title : Staurosporine-induced apoptosis is independent of p16 and p21 and achieved via arrest at G2/M and at G1 in U251MG human glioma cell line.

Pub. Date : 2003 Apr

PMID : 12721754






1 Functional Relationships(s)
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1 However, pRb was dephosphorylated and cdc2 was inhibited at both the low and the high concentrations of staurosporine, indicating that the mechanisms of cell cycle regulation are not simply p53-Rb- or cdc2-dependent pathways. Staurosporine cyclin dependent kinase 1 Homo sapiens