Pub. Date : 2003 May
PMID : 12717439
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | We report that checkpoint kinase 2 (Chk2) regulates E2F-1 activity in response to the DNA-damaging agent etoposide. | Etoposide | checkpoint kinase 2 | Homo sapiens |
2 | We report that checkpoint kinase 2 (Chk2) regulates E2F-1 activity in response to the DNA-damaging agent etoposide. | Etoposide | checkpoint kinase 2 | Homo sapiens |
3 | Moreover, E2F-1 is resistant to induction by etoposide in tumour cells expressing mutant chk2. | Etoposide | checkpoint kinase 2 | Homo sapiens |