Title : The role of p53 deacetylation in p21Waf1 regulation by laminar flow.

Pub. Date : 2003 Jul 4

PMID : 12716906






4 Functional Relationships(s)
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1 The application of a laminar flow (12 dyn/cm2) increased the deacetylation at Lys-320 and Lys-373 of p53 and the acetylation at Lys-382 in human umbilical vein endothelial cells. Lysine tumor protein p53 Homo sapiens
2 The application of a laminar flow (12 dyn/cm2) increased the deacetylation at Lys-320 and Lys-373 of p53 and the acetylation at Lys-382 in human umbilical vein endothelial cells. Lysine tumor protein p53 Homo sapiens
3 The application of a laminar flow (12 dyn/cm2) increased the deacetylation at Lys-320 and Lys-373 of p53 and the acetylation at Lys-382 in human umbilical vein endothelial cells. Lysine tumor protein p53 Homo sapiens
4 Treating human umbilical vein endothelial cells with trichostatin A (TSA), an HDAC inhibitor, abolished the flow-induced p53 deacetylation at Lys-320 and Lys-373. Lysine tumor protein p53 Homo sapiens