Title : Intraluminal pressure increases vascular neuronal nitric oxide synthase expression.

Pub. Date : 2003 May

PMID : 12714868






1 Functional Relationships(s)
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1 The ERK1/2 kinase cascade inhibitor PD 98059 significantly impaired the expression of nNOS in arteries exposed to 200 mmHg for 9 h. However, the angiotensin AT(1) antagonist candesartan and the angiotensin converting enzyme inhibitor perindoprilat did not have any effect under the same experimental conditions. candesartan mitogen activated protein kinase 3 Rattus norvegicus