Title : Evaluating the genetic toxicology of DNA-based products using existing genetic toxicology assays.

Pub. Date : 2003 May

PMID : 12714691






1 Functional Relationships(s)
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1 Two of the non-viral delivery facilitators (Effectene and ExGen 500) themselves induced mutation at the HPRT locus, although they were considerably less potent than the positive control ethyl methanesulphonate. Ethyl Methanesulfonate hypoxanthine-guanine phosphoribosyltransferase Cricetulus griseus