Title : Phagocytes produce 5-chlorouracil and 5-bromouracil, two mutagenic products of myeloperoxidase, in human inflammatory tissue.

Pub. Date : 2003 Jun 27

PMID : 12707270






1 Functional Relationships(s)
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1 In contrast, previous studies have demonstrated that 5-bromouracil could be generated by either eosinophil peroxidase or myeloperoxidase, which preferentially brominates uracil at plasma concentrations of halide and under moderately acidic conditions. halide myeloperoxidase Homo sapiens