Title : Inducible, brain region-specific expression of a dominant negative mutant of c-Jun in transgenic mice decreases sensitivity to cocaine.

Pub. Date : 2003 Apr 25

PMID : 12706249






1 Functional Relationships(s)
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1 In the present study, we took advantage of this property and generated transgenic mice, using the tetracycline gene regulation system, that support the inducible, brain region-specific expression of a dominant negative mutant form of c-Jun (Deltac-Jun), which can antagonize the actions of Fos proteins. Tetracycline jun proto-oncogene Mus musculus