Pub. Date : 2003 Apr 25
PMID : 12705905
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Guggulsterone antagonizes farnesoid X receptor induction of bile salt export pump but activates pregnane X receptor to inhibit cholesterol 7alpha-hydroxylase gene. | pregna-4,17-diene-3,16-dione | ATP binding cassette subfamily B member 11 | Homo sapiens |
| 2 | Transient transfection assay of a human BSEP/luciferase reporter in HepG2 cells transfected with FXR reveals that guggulsterone strongly antagonizes bile acid induction of the BSEP gene. | pregna-4,17-diene-3,16-dione | ATP binding cassette subfamily B member 11 | Homo sapiens |
| 3 | Transient transfection assay of a human BSEP/luciferase reporter in HepG2 cells transfected with FXR reveals that guggulsterone strongly antagonizes bile acid induction of the BSEP gene. | pregna-4,17-diene-3,16-dione | ATP binding cassette subfamily B member 11 | Homo sapiens |