Title : PKC alpha mediates maternal touch regulation of growth-related gene expression in infant rats.

Pub. Date : 2003 Jun

PMID : 12700701






2 Functional Relationships(s)
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1 Our results demonstrate that the absence of specific tactile stimuli provided by the mother limits PRL-evoked stimulation of ODC biosynthesis by interfering with sn-1,2-diacylglycerol"s (DAG) ability to activate protein kinase Calpha (PKCalpha) and consequently c-myc mRNA and max mRNA expression. sn-1,2-diacylglycerol protein kinase C alpha Homo sapiens
2 Our results demonstrate that the absence of specific tactile stimuli provided by the mother limits PRL-evoked stimulation of ODC biosynthesis by interfering with sn-1,2-diacylglycerol"s (DAG) ability to activate protein kinase Calpha (PKCalpha) and consequently c-myc mRNA and max mRNA expression. sn-1,2-diacylglycerol protein kinase C alpha Homo sapiens