Title : Involvement of SAPK/JNK in basic fibroblast growth factor-induced vascular endothelial growth factor release in osteoblasts.

Pub. Date : 2003 Apr

PMID : 12697041






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 SP600125, an inhibitor of SAPK/JNK, markedly reduced the FGF-2-induced VEGF release. pyrazolanthrone fibroblast growth factor 2 Mus musculus
2 SP600125 suppressed the FGF-2-induced phosphorylation of SAPK/JNK without affecting the phosphorylation of p44/p42 MAP kinase or p38 MAP kinase induced by FGF-2. pyrazolanthrone fibroblast growth factor 2 Mus musculus
3 A combination of SP600125 and SB203580 suppressed the FGF-2-stimulated VEGF release in an additive manner. pyrazolanthrone fibroblast growth factor 2 Mus musculus