Title : In AML cell lines Ara-C combined with purine analogues is able to exert synergistic as well as antagonistic effects on proliferation, apoptosis and disruption of mitochondrial membrane potential.

Pub. Date : 2003 Jan

PMID : 12691159






1 Functional Relationships(s)
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Protein Name
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1 The pyrimidine analogue Ara-C and the purine analogues fludarabine and cladribine (2-CdA) are essential compounds in the treatment of acute myeloid leukemia (AML). pyrimidine cytidine deaminase Homo sapiens