Title : MEK/ERK pathway is aberrantly active in Hodgkin disease: a signaling pathway shared by CD30, CD40, and RANK that regulates cell proliferation and survival.

Pub. Date : 2003 Aug 1

PMID : 12689928






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 UO126 modulated the levels of several intracellular proteins including B-cell lymphoma protein 2 (Bcl-2), myeloid cell leukemia-1 (Mcl-1) and caspase 8 homolog FLICE-inhibitory protein (cFLIP), and induced G2M cell-cycle arrest or apoptosis. U 0126 MCL1 apoptosis regulator, BCL2 family member Homo sapiens
2 UO126 modulated the levels of several intracellular proteins including B-cell lymphoma protein 2 (Bcl-2), myeloid cell leukemia-1 (Mcl-1) and caspase 8 homolog FLICE-inhibitory protein (cFLIP), and induced G2M cell-cycle arrest or apoptosis. U 0126 MCL1 apoptosis regulator, BCL2 family member Homo sapiens