Pub. Date : 2003 May 6
PMID : 12686490
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Inhibition studies with the GSTP1-1 mutants C47S, C101S and the double mutant C47S/C101S showed that cysteine 47 is the key residue in the interaction between quercetin and GSTP1-1. | Cysteine | glutathione S-transferase pi 1 | Homo sapiens |
| 2 | Inhibition studies with the GSTP1-1 mutants C47S, C101S and the double mutant C47S/C101S showed that cysteine 47 is the key residue in the interaction between quercetin and GSTP1-1. | Cysteine | glutathione S-transferase pi 1 | Homo sapiens |
| 3 | Nevertheless, the results of the present study indicate that quinone-type oxidation products of quercetin likely act as specific active site inhibitors of GSTP1-1 by binding to cysteine 47. | Cysteine | glutathione S-transferase pi 1 | Homo sapiens |