Title : Ruthenium red, inhibitor of mitochondrial Ca2+ uniporter, inhibits curcumin-induced apoptosis via the prevention of intracellular Ca2+ depletion and cytochrome c release.

Pub. Date : 2003 Apr 18

PMID : 12684045






1 Functional Relationships(s)
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1 Curcumin induces apoptosis in U937 cells via a mechanism that appears to involve down-regulation of the anti-apoptotic Bcl-xL, and IAP proteins, release of cytochrome c, and activation of caspase 3. Curcumin BCL2 like 1 Homo sapiens