Title : Protein kinase B activation by reactive oxygen species is independent of tyrosine kinase receptor phosphorylation and requires SRC activity.

Pub. Date : 2003 Jun 6

PMID : 12682076






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Exposure of cells to H2O2 rapidly increases tyrosine phosphorylation of tyrosine kinase receptors (TKRs) in the absence of growth factor binding, thus inducing the activation of downstream signaling cascades, like that of protein kinase B (AKT). Hydrogen Peroxide AKT serine/threonine kinase 1 Homo sapiens