Title : Alpha2beta1-integrin signaling by itself controls G1/S transition in a human adenocarcinoma cell line (Caco-2): implication of NADPH oxidase-dependent production of ROS.

Pub. Date : 2003 Apr 15

PMID : 12681287






1 Functional Relationships(s)
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1 NADPH oxidase activation and, therefore, the production of ROS were shown to be involved in the increase of alpha2beta1-integrin plasma membrane expression, p38 MAPK phosphorylation, cyclin expression, and G1/S transition. Reactive Oxygen Species mitogen-activated protein kinase 1 Homo sapiens